Triple negative is sometimes used as a surrogate term for basal-like ; however, more detailed classification may provide better guidance for treatment and better estimates for prognosis. Triple-negative breast cancers comprise a very heterogeneous group of cancers. There is conflicting information over prognosis for the various subtypes, but it appears that the Nottingham prognostic index is valid and hence general prognosis is rather similar with other breast cancer of same stage, except that more aggressive treatment is required.
One of these subtypes is known as triple-negative breast cancer TNBC. TNBC grows rapidly. It also has a higher grade and tends to metastasize spread.
Women of color and young women may face elevated risks of developing triple-negative breast cancers, a type of cancer that spreads more quickly than most other types and doesn't respond well to hormone or targeted therapies, a study published in CANCERa peer-reviewed journal of the American Cancer Society, shows. Previous U. To conduct a larger study, researchers in the Georgia State University School of Public Health analyzed all breast cancer cases diagnosed during from the United States Cancer Statistics database, a surveillance system of cancer registries with data representing 99 percent of the U.
And if it turns out you have triple negative breast cancertreatment can become even more complex for your doctors—and confusing for you as the patient. To hopefully make things a little easier to understand, we spoke to experts on the frontlines to find out what you really need to know about triple negative breast cancer treatment. While the best source of information about your individual case is always going to be your care team, consider this a resource for getting yourself oriented. One important method for classifying this disease is based on the types of receptors or proteins the cancer cells might have, which can affect how the cancer grows in your body, the American Cancer Society ACS explains.
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There are several subsets of triple negative breast cancer. One subset is basal-like. Basal-like tumors have cells with features similar to those of the outer basal cells surrounding the mammary ducts.
Triple negative breast cancer is a type of breast cancer that does not have any of the three receptors commonly found on breast cancer cells — the oestrogen, progesterone and HER2 receptors. Triple negative breast cancer generally responds well to chemotherapy. Five years after diagnosis, people with triple negative breast cancer are no more likely to experience a recurrence of their breast cancer than people with other types of breast cancer.
Some questions you may have are:. The answer to those and other questions you have will depend on a lot of factors, such as the stage of the cancer and how well it responds to treatment. Keep reading to learn more about TNBC and your outlook. The outlook for breast cancer is often described in terms of five-year survival rates.